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Alexandra Rucavado Selected Research

Wounds and Injuries (Trauma)

9/2022Longitudinal Metabolomics and Lipidomics Analyses Reveal Alterations Associated with Envenoming by Bothrops asper and Daboia russelii in an Experimental Murine Model.
10/2020Analysis of wound exudates reveals differences in the patterns of tissue damage and inflammation induced by the venoms of Daboia russelii and Bothrops asper in mice.
1/2012Efficacy of IgG and F(ab')2 antivenoms to neutralize snake venom-induced local tissue damage as assessed by the proteomic analysis of wound exudate.
4/2011Proteomics of wound exudate in snake venom-induced pathology: search for biomarkers to assess tissue damage and therapeutic success.
11/2009Wound exudate as a proteomic window to reveal different mechanisms of tissue damage by snake venom toxins.

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Alexandra Rucavado Research Topics

Disease

31Hemorrhage
10/2023 - 04/2002
15Snake Bites (Snake Bite)
10/2023 - 10/2003
11Edema (Dropsy)
07/2021 - 04/2002
8Thrombocytopenia (Thrombopenia)
10/2023 - 10/2003
5Inflammation (Inflammations)
02/2024 - 01/2020
5Wounds and Injuries (Trauma)
09/2022 - 11/2009
4Necrosis
10/2023 - 01/2011
4Thrombosis (Thrombus)
04/2023 - 10/2003
3Myotoxicity
01/2018 - 10/2008
2Fibrosis (Cirrhosis)
02/2024 - 01/2011
2Disseminated Intravascular Coagulation
10/2023 - 07/2022
2Shock
10/2020 - 12/2009
2Blister (Bulla)
01/2019 - 10/2008
2Hemolysis
10/2017 - 03/2007
2Hypovolemia
01/2015 - 12/2009
2Rupture
01/2006 - 02/2005
1Brucellosis (Malta Fever)
03/2022
1Acute Lung Injury
07/2021
1Joint Diseases (Joint Disease)
01/2020
1Atrophy
01/2018
1Hypoxia (Hypoxemia)
01/2018
1Bites and Stings (Sting)
06/2017
1Infections
01/2016
1Melanoma (Melanoma, Malignant)
12/2014
1Ischemia
12/2009
1Bacterial Infections (Bacterial Infection)
12/2009
1Sudden Death
10/2003

Drug/Important Bio-Agent (IBA)

32VenomsIBA
02/2024 - 10/2003
22Metalloproteases (Metalloproteinases)IBA
07/2021 - 10/2003
17Snake Venoms (Snake Venom)IBA
11/2022 - 11/2003
9Proteins (Proteins, Gene)FDA Link
11/2022 - 10/2008
6Antivenins (Antivenoms)IBA
10/2023 - 01/2007
5batimastat (BB 94)IBA
06/2017 - 04/2002
4EnzymesIBA
07/2021 - 10/2003
4Laminin (Merosin)IBA
03/2021 - 10/2008
4Collagen Type IV (Type IV Collagen)IBA
03/2021 - 10/2008
4Peptide Hydrolases (Proteases)FDA Link
01/2019 - 11/2003
3aspercetinIBA
11/2022 - 07/2005
3Extracellular Matrix ProteinsIBA
12/2014 - 11/2009
3estropipate (Ogen)FDA LinkGeneric
03/2013 - 07/2005
2C-Type Lectins (C-Type Lectin)IBA
11/2022 - 12/2009
2Saline SolutionIBA
11/2022 - 01/2006
2Matrix Metalloproteinases (MMPs)IBA
01/2020 - 04/2002
2Phospholipases A2 (Phospholipase A2)IBA
06/2018 - 11/2009
2CoagulantsIBA
10/2016 - 10/2008
2Fibronectins (Fibronectin)IBA
12/2014 - 11/2009
2AntibodiesIBA
12/2009 - 03/2007
2Phospholipases (Phospholipase)IBA
11/2009 - 10/2008
2Bothrops jararaca VenomIBA
07/2005 - 11/2003
2PeptidomimeticsIBA
03/2004 - 04/2002
1Transforming Growth Factors (Transforming Growth Factor)IBA
02/2024
1DesminIBA
10/2023
1Viper Venoms (Viper Venom)IBA
04/2023
1CytokinesIBA
03/2022
1Indomethacin (Indometacin)FDA LinkGeneric
07/2021
1Pentoxifylline (Trental)FDA LinkGeneric
07/2021
1Complement System Proteins (Complement)IBA
01/2021
1ProteomeIBA
01/2019
1Hyaluronoglucosaminidase (Hyaluronidase)FDA Link
10/2017
1perlecanIBA
04/2016
1trimethylaminocarboxyldihydroboran (TCDB)IBA
01/2016
1Hemoglobins (Hemoglobin)IBA
04/2015
1nidogen (entactin)IBA
04/2015
1Collagen Type VIIBA
04/2015
1VitronectinIBA
12/2014
1Collagen Type I (Type I Collagen)IBA
12/2014
1DisintegrinsIBA
12/2014
1Toxic ActionsIBA
09/2013
1glycolic acid (glycolate)IBA
09/2013
1Creatine Kinase (Creatine Phosphokinase)IBA
09/2013
1Fibrinogen (Factor I)FDA Link
03/2013
1FibrinIBA
03/2013
1fibrin fragment D (D-dimer)IBA
03/2013
1Serine Proteases (Serine Protease)IBA
03/2013
1ZincIBA
07/2012
1Immunoglobulin G (IgG)IBA
01/2012
1Biomarkers (Surrogate Marker)IBA
04/2011
1Synthetic DrugsIBA
12/2009
1Hemostatics (Antihemorrhagics)IBA
12/2009
1Non-Fibrillar CollagensIBA
11/2009
1ApolipoproteinsIBA
11/2009
1Apolipoproteins AIBA
11/2009
1Fibrillar CollagensIBA
11/2009
1Doxycycline (Periostat)FDA LinkGeneric
12/2008
1Clodronic Acid (Clodronate)IBA
12/2008
1DNA (Deoxyribonucleic Acid)IBA
02/2005
1Blood Proteins (Serum Proteins)IBA
11/2003
1Prothrombin (Factor II)IBA
10/2003
1Metallothionein 3IBA
04/2002
1Matrix Metalloproteinase InhibitorsIBA
04/2002

Therapy/Procedure

3Therapeutics
01/2021 - 01/2007
3Intravenous Administration
07/2005 - 10/2003
2Intravenous Injections
07/2021 - 07/2005